Symptom-Level Network Analysis Distinguishes Unique Associations of Repetitive Negative Thinking and Experiential Avoidance with Depression and Anxiety in a Transdiagnostic Clinical Sample

Repetitive negative thinking and experiential avoidance have been hypothesized to be related, transdiagnostic maintenance factors for depression anxiety, yet is unclear how these processes overlap or diverge. Here we use a symptom-level approach address this question. Adults presenting treatment an intensive CBT program (n = 492) completed measures of anxiety symptom severity, repetitive thinking, avoidance. Our pre-registered network analysis examined the contribution predictability network. Exploratory analyses used permutation testing formally evaluate Permutation indicates that significantly improved worrying poor concentration, whereas difficulties relaxing, being afraid something bad was going happen, feeling like failure. sample cross-sectional predominantly white, educated, industrialized, rich, democratic (WEIRD) sample. each were associated with symptoms but did not across comorbid More broadly, applying helps more precisely identify which are factors, thus providing insight into may contribute co-occurring disorders.